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Chelation-controlled stannylacetylene additions to β-alkoxy aldehydes promoted by alkylaluminum halide Lewis acids

✍ Scribed by David A. Evans; David P. Halstead; Brett D. Allison

Book ID
104261523
Publisher
Elsevier Science
Year
1999
Tongue
French
Weight
146 KB
Volume
40
Category
Article
ISSN
0040-4039

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✦ Synopsis

Lewis acid-mediated additions of stannylacetylenes to I]-alkoxy aldehydes are reported. High levels of chelation control are observed with dimethylaluminum chloride (Me2AICI) and methylaluminum dichloride (MeA1C12).

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Lewis acid promoted aldol additions of α
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✍ Anna Bernardi; Silvia Cardani; Cesare Gennari; Giovanni Poli; Carlo Scolastico 📂 Article 📅 1985 🏛 Elsevier Science 🌐 French ⚖ 190 KB

MgBr mediated addition of to A'and Methyl &-methylthio propionate silylketene acetal o(,p-alkoxy aldehydes is highly 3,4 syn-selective (18:l). syn-d-methylene$-hydroxy-s-alkoxy esters (6) and (8) are synthesized. We recently reported that I butyIP-dimethylamino propionate, a synthetic equivalent of