Negatively Charged Polymers Protect Anti
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Gennady P. Samokhin; Dmitry A. Mongayt; Leonid Z. Iakoubov; Tatyana S. Levchenko
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Article
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2001
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Elsevier Science
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English
β 67 KB
For many practical applications, monoclonal antibodies must be chemically modified without any significant loss in their immunoreactivity. In some situations, however, the amino acid residue crucial for antibody activity may be highly reactive toward the modifying agent, which results in antibody in