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CHEK2contribution to hereditary breast cancer in non-BRCAfamilies

✍ Scribed by Alexis Desrichard; Yannick Bidet; Nancy Uhrhammer; Yves-Jean Bignon

Book ID
118726827
Publisher
BioMed Central
Year
2011
Tongue
English
Weight
388 KB
Volume
13
Category
Article
ISSN
1465-5411

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✍ Michael R. Dufault; Beate Betz; Barbara Wappenschmidt; Wera Hofmann; Katrin Band πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 French βš– 215 KB πŸ‘ 2 views

## Abstract To establish the importance of __CHEK2__ mutations for familial breast cancer incidence in the German population, we have screened all 14 of the coding exons in 516 families negative for mutations in both the __BRCA1__ and __BRCA2__ genes. We found 12 distinct variants in 30 unrelated p