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Checks and Balances between Cohesin and Polycomb in Gene Silencing and Transcription

✍ Scribed by Dorsett, Dale; Kassis, Judith A.

Book ID
124123844
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
394 KB
Volume
24
Category
Article
ISSN
0960-9822

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## Abstract Epigenetic regulation is involved in the maintenance of long‐term silencing phenomena, such as X‐inactivation and genomic imprinting in mammals. Gene repression is mediated by several mechanisms, such as histone modifications, DNA methylation, and recruitment of Polycomb proteins. To un