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Checkpoints in thymocytopoiesis in aging: expression of the recombination activating genes RAG-1 and RAG-2

✍ Scribed by Arie Ben Yehuda; Gideon Friedman; Eitan Wirtheim; Loya Abel; Amiela Globerson


Book ID
114096533
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
131 KB
Volume
102
Category
Article
ISSN
0047-6374

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Recombination activating gene 1 (Rag1) i
✍ Patricia Greenhalgh; Lisa A. Steiner πŸ“‚ Article πŸ“… 1995 πŸ› Springer-Verlag 🌐 English βš– 150 KB

Two closely-linked genes, Ragl and Rag2, are required for the recombination of V, D, and J gene segments to form the genes encoding V regions of Igs and T-cell receptors. In several mammalian species, chickens, and Xenopus laevis, the coding region of RAG1 lies within a single exon; its sequence is