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Checkpoint deficient rad53-11 yeast cannot accumulate dNTPs in response to DNA damage

✍ Scribed by Ahmet Koc; Gary F. Merrill


Book ID
116294118
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
121 KB
Volume
353
Category
Article
ISSN
0006-291X

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## Abstract After irradiation, ATM defective cells accumulate unrepaired double strand breaks (DSBs) for several cell divisions. At the chromosome level, unresolved DSBs appear as chromosome breaks that can be efficiently scored by using telomeric and mFISH probes. H2AX is immediately activated by