Breaks invisible to the DNA damage respo
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Marta MartΓn; Mariona Terradas; George Iliakis; Laura Tusell; Anna GenescΓ
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Article
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2009
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John Wiley and Sons
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English
β 870 KB
## Abstract After irradiation, ATM defective cells accumulate unrepaired double strand breaks (DSBs) for several cell divisions. At the chromosome level, unresolved DSBs appear as chromosome breaks that can be efficiently scored by using telomeric and mFISH probes. H2AX is immediately activated by