𝔖 Bobbio Scriptorium
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Charybdotoxin, a protein inhibitor of single Ca2+-activated K+ channels from mammalian skeletal muscle

✍ Scribed by Miller, Christopher; Moczydlowski, Edward; Latorre, Ramon; Phillips, Marcia


Book ID
109737889
Publisher
Nature Publishing Group
Year
1985
Tongue
English
Weight
326 KB
Volume
313
Category
Article
ISSN
0028-0836

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Solution structure of TsKapa, a charybdo
✍ E. Blanc; C. Lecomte; J. Van Rietschoten; J.M. Sabatier; H. Darbon πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 802 KB

TsKapa (TsK), purified from the Buthidae Tityus serrulatus is a very high potent ligand for small-conductance apaminsensitive calcium-activated potassium channels (SK). It is able to efficiently compete with apamin for binding on this channel (K 0.5 ‫؍‬ 0.3 nM) [Legros, C. et al., FEBS Lett. 390:81-