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Charge State Distribution and Hydrogen/Deuterium Exchange of α-Lactalbumin and β-Lactoglobulin Preparations by Electrospray Ionization Mass Spectrometry

✍ Scribed by Alomirah, Husam; Alli, Inteaz; Konishi, Yasuo


Book ID
127096503
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
204 KB
Volume
51
Category
Article
ISSN
0021-8561

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✍ David S. Wagner; Laura G. Melton; Yibing Yan; Bruce W. Erickson; Robert J. Ander 📂 Article 📅 1994 🏛 Cold Spring Harbor Laboratory Press 🌐 English ⚖ 985 KB

## Abstract Deuterium exchange was monitored by electrospray ionization mass spectrometry (ESI‐MS) to study the slowly exchanging (hydrogen bonded) peptide hydrogens of several α‐helical peptides and β‐sheet proteins. Polypeptides were synthetically engineered to have mainly disordered, α‐helical,