Deuterium exchange of α-helices and β-sh
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David S. Wagner; Laura G. Melton; Yibing Yan; Bruce W. Erickson; Robert J. Ander
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Article
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1994
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Cold Spring Harbor Laboratory Press
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English
⚖ 985 KB
## Abstract Deuterium exchange was monitored by electrospray ionization mass spectrometry (ESI‐MS) to study the slowly exchanging (hydrogen bonded) peptide hydrogens of several α‐helical peptides and β‐sheet proteins. Polypeptides were synthetically engineered to have mainly disordered, α‐helical,