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Charge-charge and cation-πinteractions in ligand binding to G protein-coupled receptors

✍ Scribed by N. Dölker; X. Deupi; L. Pardo; M. Campillo


Book ID
105886125
Publisher
Springer
Year
2007
Tongue
English
Weight
344 KB
Volume
118
Category
Article
ISSN
1432-2234

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✍ Marcel L. Verdonk; Gertjan J. Boks; Huub Kooijman; Jan A. Kanters; Jan Kroon 📂 Article 📅 1993 🏛 Springer Netherlands 🌐 English ⚖ 484 KB

Recently, new evidence was found for the involvement of charged nitrogen-aromatic interactions in ligand-receptor binding. In this study we report two favourable orientations of a phenyl ring with respect to a R-N+(CH3)3 group, based on crystal structure statistics from the Cambridge Structural Data