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Charcot–Marie–Tooth 1B caused by expansion of a familial myelin protein zero (MPZ) gene duplication

✍ Scribed by Speevak, Marsha D.; Farrell, Sandra A.


Book ID
121379923
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
506 KB
Volume
56
Category
Article
ISSN
1769-7212

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Myelin protein zero (MPZ) gene mutations
✍ Benjamin B. Roa; Laura E. Warner; Carlos A. Garcia; Donna Russo; Robert Lovelace 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 975 KB

The myelin protein zero gene (MPZ) maps to chromosome lq22-23 and encodes the most abundant peripheral nerve myelin protein. The Po protein functions as a homophilic adhesion molecule in myelin compaction. Mutations in the MPZ gene are associated with the demyelinating peripheral neuropathies Charco