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Characterization with [3H]quisqualate of group I metabotropic glutamate receptor subtype in rat central and peripheral excitable tissues

✍ Scribed by Eiichi Hinoi; Kiyokazu Ogita; Yutaka Takeuchi; Hiroshi Ohashi; Takaharu Maruyama; Yukio Yoneda

Book ID
117409585
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
267 KB
Volume
38
Category
Article
ISSN
0197-0186

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While it is well documented that the overactivation of ionotropic glutamate receptors leads to seizures and excitotoxic injury, little is known about the role of metabotropic glutamate receptors (mGluRs) in epileptogenesis and neuronal injury. Intracerebroventricular (i.c.v.) infusion of the group I