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Characterization of α-synuclein aggregation and synergistic toxicity with protein tau in yeast

✍ Scribed by Piotr Zabrocki; Klaartje Pellens; Thomas Vanhelmont; Tom Vandebroek; Gerard Griffioen; Stefaan Wera; Fred Van Leuven; Joris Winderickx

Book ID
111309894
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
755 KB
Volume
272
Category
Article
ISSN
1432-1327

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## Abstract Parkinson's disease (PD) is generally sporadic but a number of genetic diseases have parkinsonism as a clinical feature. Two dominant genes, α‐synuclein (__SNCA__) and leucine‐rich repeat kinase 2 (__LRRK2__), are important for understanding inherited and sporadic PD. __SNCA__ is a majo