A temperature-sensitive cell cycle mutan
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Stuart J. Burstin; Harriet K. Meiss; Claudio Basilico
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Article
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1974
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John Wiley and Sons
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English
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## Abstract A temperatureβsensitive growth mutant derived from the BHK 21 cell Line, ts AF8, was found to have greatly reduced DNA synthesis at the nonpermissive temperature. This reduction is mainly due to a decrease in the frequency of cells synthesizing DNA. Upon shift up, ts AF8 becomes blocked