## Abstract Trabecular bone structure is known to play a crucial role in the overall strength, and thus fracture risk, of such areas of the skeleton as the vertebrae, spine, femur, tibiae, or radius. Several MR methods devoted to probing this structure depend upon the susceptibility difference betw
Characterization of trabecular bone by dipolar demagnetizing field MRI
β Scribed by Silvia Capuani; Francesca Curzi; Francesco Maria Alessandri; Bruno Maraviglia; Angelo Bifone
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 288 KB
- Volume
- 46
- Category
- Article
- ISSN
- 0740-3194
- DOI
- 10.1002/mrm.1246
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β¦ Synopsis
Abstract
A multiple spinβecho (MSE) sequence has been applied for the first time to study trabecular bone ex vivo. The second echo generated by the demagnetizing field presents discrete drops in signal intensity for certain values of the pitch of the magnetization helix created by the correlation gradient. These dips may reflect characteristic pore sizes in the trabecular bone specimens. This hypothesis is supported by similar experiments performed on a phantom with uniform pore size distribution. Trabecular bone images weighted in the MSE contrast mechanism are reported. Magn Reson Med 46:683β689, 2001. Β© 2001 WileyβLiss, Inc.
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## Abstract ## Purpose: To characterize the DDIF (Decay due to Diffusion in the Internal Field) method using intact animal trabecular bone specimens of varying trabecular structure and porosity, under ex vivo conditions closely resembling in vivo physiological conditions. The DDIF method provides