Mutant protein of recombinant human gran
Mutant protein of recombinant human granulocyte colony-stimulating factor for receptor binding assay
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Masahiko Watanabe; Hiromi Fukamachi; Hiroya Uzumaki; Koji Kabaya; Haruhiko Tsumu
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Article
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1991
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Elsevier Science
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English
β 801 KB
A new mutant protein of recombinant human granulocyte colony-stimulating factor (rhG-CSF) was produced for the studies on receptors for human G-CSF. The mutant protein [(Tyr1, Tyr3]rhG-CSF), the biological activity of which was almost equal to that of rhG-CSF, was prepared by the replacement of thre