Chromosome I rearrangements involving th
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Angela Greco; Claudia Miranda; Sonia Pagliardini; Lisa Fusetti; Italia Bongarzon
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Article
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1997
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John Wiley and Sons
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English
β 195 KB
The NTRK1 gene in the q arm of chromosome 1 encodes one of the receptors for the nerve growth factor and is frequently activated as an oncogene in papillary thyroid carcinomas. The activation is due to chromosomal rearrangements juxtaposing the NTRK1 tyrosine kinase domain to 58-end sequences from d