Characterization of a novel interaction
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Catarina SacristΓ‘n; Stefan A. Schattgen; Leslie J. Berg; Stephen C. Bunnell; Ana
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Article
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2009
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John Wiley and Sons
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English
β 354 KB
π 1 views
## Abstract TCR signaling leads to the activation of kinases such as inducible tyrosine kinase (Itk), a key regulatory protein in Tβlymphocyte activation and function. The homolog of Itk in B cells is Bruton's tyrosine kinase, previously shown to bind and phosphorylate the transcription factor TFII