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Characterization of the mucopolysaccharides associated with fractions of guanidine-denatured amyloid fibrils

โœ Scribed by Kenneth D. Brandt; Martha Skinner; Alan S. Cohen

Book ID
115820161
Publisher
Elsevier Science
Year
1974
Tongue
English
Weight
820 KB
Volume
55
Category
Article
ISSN
0009-8981

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## Abstract Amyloidโ€ฮฒ peptide (Aฮฒ) is the principal constituent of plaques associated with Alzheimer's disease (AD) and is thought to be responsible for the neurotoxicity associated with the disease. Copper binding to Aฮฒ has been hypothesized to play an important role in the neruotoxicity of Aฮฒ and