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Characterization of the mechanisms of busulfan resistance in a human glioblastoma multiforme xenograft

โœ Scribed by C. Bradley Hare; Gertrude B. Elion; O. Michael Colvin; Francis Ali-Osman; Owen W. Griffith; William P. Petros; Stephen Keir; Susan L. Marcelli; Darell D. Bigner; Henry S. Friedman


Book ID
105994247
Publisher
Springer
Year
1997
Tongue
English
Weight
601 KB
Volume
40
Category
Article
ISSN
0344-5704

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Using the technique of DD-PCR (differential displaypolymerase chain reaction) we isolated a novel gene (D2-2) that is overexpressed in glioblastoma multiforme tissue (GMT) as compared to normal brain tissue (NBT). D2-2 is also highly expressed in recurrent glioma, colon tumor metastatic to brain, br