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Characterization of the gene for human EMMPRIN, a tumor cell surface inducer of matrix metalloproteinases

✍ Scribed by Huiming Guo; Gopa Majmudar; Timothy C Jensen; Chitra Biswas; Bryan P Toole; Marion K Gordon

Book ID: 117523298
Publisher: Elsevier Science
Year: 1998
Tongue: English
Weight: 467 KB
Volume: 220
Category: Article
ISSN: 0378-1119
DOI: 10.1016/s0378-1119(98)00400-4

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EMMPRIN (extracellular matrix metalloproteinase inducer), also called CD147, basigin or M6 in the human, is a member of the immunoglobulin superfamily that is present on the surface of tumor cells and stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPs). In our study, we inves

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