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Characterization of the Fugu rubripes NLK and FN5 genes flanking the NF1 (Neurofibromatosis type 1) gene in the 5′ direction and mapping of the human counterparts

✍ Scribed by Hildegard Kehrer-Sawatzki; Elke Moschgath; Christiane Maier; Eric Legius; Greg Elgar; Winfrid Krone


Book ID
117519870
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
526 KB
Volume
251
Category
Article
ISSN
0378-1119

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We studied 20 unrelated NF1 patients by Southern blots with seven cDNA probes and loss of heterozygosity (LOH) analysis with four intragenic microsatellites (IVS26-2.3, IVS27AC28.4, IVS27AC33.1, and IVS38GT53.0). Four novel large deletions (178, 184, 236, and 237) have been identified and characteri