Characterization of the DNA Binding Features of Saccharomyces castellii Cdc13p
β Scribed by J. Rhodin; E. Astromskas; M. Cohn
- Book ID
- 116662613
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 521 KB
- Volume
- 355
- Category
- Article
- ISSN
- 0022-2836
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Production of recombinant proteins can be valuable in studying their biological functions. However, recombinant proteins expressed in Escherichia coli sometimes form undesirable insoluble aggregates. Solubilization and renaturation of these aggregates becomes a problem that one needs to solve. Here
## Abstract **Background:** DNA polymerase Ι (Pol Ι) of __Saccharomyces cerevisiae__ participates in many aspects of DNA replication, as well as in DNA repair. In order to clarify molecular mechanisms employed in the multiple tasks of Pol Ι, we have been characterizing the interaction between Pol Ι