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Characterization of the cyclin-dependent kinase inhibitory domain of the INK4 family as a model for a synthetic tumour suppressor molecule

✍ Scribed by Fåhraeus, Robin; Laín, Sonia; Ball, Kathryn L; Lane, David P

Book ID: 110061138
Publisher: Nature Publishing Group
Year: 1998
Tongue: English
Weight: 452 KB
Volume: 16
Category: Article
ISSN: 0950-9232
DOI: 10.1038/sj.onc.1201580

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## Abstract Granulosa cell tumors (GCTs) of the ovary are relatively rare and account for <5% of all ovarian cancers. The molecular pathogenesis of these tumors is not well understood. We tested the hypothesis that cyclin‐dependent kinase inhibitors, specifically the __in__hibitors of the cyclin‐de