The effects of low (10-100 ~M) concentrations of tetracaine on intramembrane charge movement and on the rate of calcium release (RreI) from the sarcoplasmic reticulum (SR) were studied in cut skeletal muscle fibres of the frog using the voltage clamp technique. The fibres were mounted in a single or
Characterization of the calcium release domains during excitation-contraction coupling in skeletal muscle fibres
✍ Scribed by Marino DiFranco; David Novo; Julio L. Vergara
- Publisher
- Springer
- Year
- 2001
- Tongue
- English
- Weight
- 371 KB
- Volume
- 443
- Category
- Article
- ISSN
- 0031-6768
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Using the sucrose vaseline gap technique, experiments were carried out on isolated flog twitch muscle fibre to investigate the role of chloride ions in excitation-contraction coupling. In current clamp conditions, replacement of chloride ions by impermeant anions led to an increase of the amplitude
The effects of the dihydropyridine derivative, nifedipine, well known as a blocker of calcium channels, were tested on cultured rat myoballs. Membrane currents and contractions were simultaneously recorded by means of the patch-clamp technique and a photoelectric transducing method. High concentrati