Characterization of the bioactive form and molecular determinants of recognition of cyclic enkephalin peptides at the δ-opioid receptor

Characterization of the bioactive form o

Characterization of the bioactive form of linear peptide antagonists at the δ-opioid receptor

✍ Tain-Ming Chao; Juan J. Perez; Gilda H. Loew 📂 Article 📅 1996 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 817 KB

The strreochrmicul requirements for 6-opioid receptor binding q f a serie.r of linear pepti& antugoni.m with a novel conformationally restricted Phe analogue (Tic) as a second rcsiduluc wcw examined by using a variety qfcomputational chemistry methods. The 6-opioid receptor una-1ogue.s with signific