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Characterization of the Binding of Factor Xa to Fibrinogen/Fibrin Derivatives and Localization of the Factor Xa Binding Site on Fibrinogen

✍ Scribed by Masaki Iino; Hiroyuki Takeya; Tetsushi Takemitsu; Tomohiro Nakagaki; Esteban C. Gabazza; Koji Suzuki

Book ID
115131712
Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
839 KB
Volume
232
Category
Article
ISSN
1432-1327

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The affinities of Factor XIII (FXIII), Factor XIIIa (FXIIIa), and cellular transglutaminase (Tg) for fibrinogen (Fgn), fibrin (Fbn), and fibronectin (Fn) were compared using a solid-phase binding assay. Initial rates of binding were as follows: FXIII bound Fbn 3-fold more than Fgn. FXIII did not bin