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Characterization of the binding of benzodiazepines to human serum albumin

✍ Scribed by W. Müller; U. Wollert


Book ID
118287871
Publisher
Springer-Verlag
Year
1973
Tongue
English
Weight
426 KB
Volume
280
Category
Article
ISSN
0028-1298

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2,3-Benzodiazepines containing a centre of asymmetry at C-5 possess both central and helical chiralities, and the solution of their racemates contains four molecular species. The binding of these compounds to human serum albumin (HSA) was studied by affinity chromatography. The binding strength depe