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Characterization of the beta adrenergic system in adult rat hypertrophied hearts

โœ Scribed by P. Mansier; B. Chevalier; B. Swynghedauw


Book ID
118916873
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
111 KB
Volume
21
Category
Article
ISSN
0022-2828

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Incubation of rocker-cultured neonatal rat heart cells with 3 mM L(+)-lactate led to a sharp increase in the sensitivity of cardiomyocytes to the beta-adrenergic agonist isoprenaline, as measured by their chronotropic response. This effect was accompanied by a reduction in the arachidonic acid conte