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Characterization of the AT180 epitope of phosphorylated Tau protein by a combined nuclear magnetic resonance and fluorescence spectroscopy approach

✍ Scribed by Laziza Amniai; Guy Lippens; Isabelle Landrieu


Book ID
116302242
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
325 KB
Volume
412
Category
Article
ISSN
0006-291X

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## Abstract Phosphorylation of the neuronal Tau protein is implicated in both the regulation of its physiological function of microtubule stabilization and its pathological propensity to aggregate into the fibers that characterize Alzheimer's diseased neurons. However, how specific phosphorylation