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Characterization of the alternate allelic forms of human PAX7

✍ Scribed by Mel R. Ziman; Janelle T. Pelham; Frank L. Mastaglia; Peter H. Kay

Book ID
106015757
Publisher
Springer-Verlag
Year
2000
Tongue
English
Weight
425 KB
Volume
11
Category
Article
ISSN
0938-8990

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## Abstract __PAX3__ and __PAX7__ encode transcription factors implicated in the pathogenesis of rhabdomyosarcoma (RMS), including alveolar RMS in which chromosomal translocations generate __PAX3‐FKHR__ and __PAX7‐FKHR__ fusions. Previous studies of wild‐type PAX3 and PAX7 identified alternative sp