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Characterization of targeting domains by sequence analysis: glycogen-binding domains in protein phosphatases

✍ Scribed by Peer Bork; Thomas Dandekar; Frank Eisenhabe; Martijn Huynen

Book ID
105797370
Publisher
Springer
Year
1998
Tongue
English
Weight
180 KB
Volume
76
Category
Article
ISSN
0946-2716

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A phosphoinositide-binding sequence is s
A phosphoinositide-binding sequence is shared by PH domain target moleculesβ€”a model for the binding of PH domains to proteins
✍ Saverio Alberti πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 326 KB πŸ‘ 1 views

Pleckstrin homology (PH) domains have been proven to bind phosphoinositides (PI) and inositolphosphates (IP). On the other hand, a binding of PH domains to proteins is still a matter of debate. The goal of this work was to identify potential PH domain protein target sites and to build a model for PH