Characterization of surface-modified polyurethane blends, poly(vinyl alcohol), and poly(4-hydroxybutyl acrylate) for biomedical application by electron spin resonance spectroscopy
✍ Scribed by Günter Lorenz; Doris Klee; Hartwig Höcker; Christian Mittermayer
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- English
- Weight
- 807 KB
- Volume
- 57
- Category
- Article
- ISSN
- 0021-8995
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✦ Synopsis
Two polyurethane blends-poly(carbonate urethane)/poly (vinyl alcohol) [PCU/PVA] and the aliphatic poly(ether urethane) (Tecoflex@)/poly(pentanedioic acid mono-4-(acryl-oy1oxy)butyl ester) [Tecoflex@/COOH]-were surface-modified. Poly(viny1 alcohol) [ PVA] and poly(4-hydroxybutyl acrylate) [PHBA] were used as model surfaces. 4-Isocyanate butanoic acid methyl ester was coupled as a spacer molecule to PVA and the PVA-containing polyurethane blend. Saponification of the generated ester group was verified by means of Electron Spin Resonance (ESR) spectroscopy using the nitroxyl radical 4-amino-2,2,6,6tetramethylpiperidine-1-oxyl (4-amino-TEMPO) as a reporter group. In the case of Tecoflexm and PHBA, glutaric anhydride served as a spacer molecule. 4-Amino-TEMPO was coupled to this spacer as well. ESR spectroscopy as a bulk method was used together with the surface-sensitive method X-Ray Photoelectron Spectroscopy (XPS) verifying the modification steps by elemental composition, ESR line shapes, and determination of the rotational correlation time T,.