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Characterization of solubilized dopamine receptors from dog striatum

โœ Scribed by H. Gorissen; G. Aerts; P. Laduron


Book ID
115909587
Publisher
Elsevier Science
Year
1979
Tongue
English
Weight
478 KB
Volume
100
Category
Article
ISSN
0014-5793

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Dopamine transporter: Solubilization fro
โœ Robert Lew; Dimitri E. Grigoriadis; John Sharkey; Michael J. Kuhar ๐Ÿ“‚ Article ๐Ÿ“… 1989 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 443 KB

3H-GBR 12935 was used to label the digitonin-solubilized dopamine transporter from dog caudate nucleus. Specific binding to soluble fractions was observed in dog caudate but was absent in rat cerebellum. Binding to the solubilized transporter sites was saturable and of high affinity (Bmm = 2.57 -+ 0