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Characterization of Single-Cell Electroporation by Using Patch-Clamp and Fluorescence Microscopy

✍ Scribed by Ryttsén, Frida; Farre, Cecilia; Brennan, Carrie; Weber, Stephen G.; Nolkrantz, Kerstin; Jardemark, Kent; Chiu, Daniel T.; Orwar, Owe

Book ID
118513632
Publisher
Biophysical Society
Year
2000
Tongue
English
Weight
271 KB
Volume
79
Category
Article
ISSN
0006-3495

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Cyclic nucleotides play a central role in the modulation of ion channels in a variety of tissues, including the heart. In order to determine the possible role of cyclic GMP (cGMP) in the regulation of the background K channel activity of cardiac cells, the effect of 8-Br-cGMP on the inwardly-rectify