Characterization of salicylate binding to synovial fluid and plasma protein in patients with rheumatoid arthritis
✍ Scribed by Z. Trnavská; K. Trnavský
- Publisher
- Springer
- Year
- 1980
- Tongue
- English
- Weight
- 440 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0031-6970
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## CETYLSALICYLIC ACID ( ASA) has been A used for the treatment of rheumatoid arthritis for many years. Until recently, however, no methods have been available for the direct measurement of ASA in body fluids. Therefore, most of the data on the metabolism and distribution of ASA have been obtained
A cofactor that selectively opsonizes particulate activators of the human alternative complement pathway and enhances their phagocytosis by human monocytes was identified in synovial fluids of patients with rheumatoid arthritis. The active material was present in fluids treated with protease inhibit