## Abstract Retinoic acid inducible geneβI (RIGβI) functions as the first line of defense against viral infection by sensing dsRNA and inducing type I interferon (IFN) production. The expression of RIGβI itself is induced by IFNβΞ±/Ξ² and dsRNA. To comprehend the molecular mechanism of expression reg
β¦ LIBER β¦
Characterization of retinoic acid-inducible gene-I (RIG-I) expression corresponding to viral infection and UVB in human keratinocytes
β Scribed by Kimura, Kazuyuki; Matsuzaki, Yasushi; Nishikawa, Yohei; Kitamura, Hideo; Akasaka, Eijiro; Rokunohe, Daiki; Nakano, Hajime; Imaizumi, Tadaatsu; Satoh, Kei; Sawamura, Daisuke
- Book ID
- 119293824
- Publisher
- Elsevier Science
- Year
- 2012
- Tongue
- English
- Weight
- 793 KB
- Volume
- 66
- Category
- Article
- ISSN
- 0923-1811
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## Abstract Dendritic cells utilize various sets of Tollβlike receptors (TLR) or cytosolic sensors to detect pathogens and evoke immune responses. In patients with hepatitis C virus (HCV) infection, a higher prevalence of various infectious diseases is reported; suggesting that innate immunity agai