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Characterization of repair inhibition by methotrexate of ethylmethanesulfonate-and ultraviolet irradiation-induced DNA damage in Chinese hamster cells

โœ Scribed by Alexander H. Borchers; James A. Straw


Book ID
115781635
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
558 KB
Volume
40
Category
Article
ISSN
0006-2952

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We have studied the effect of pentoxifyhe (PTX) on DNA repair after ultraviolet radiation 0 in Chinese hamster ovary cells (CHO). DNA repair of cyclobutane pyrimidine dimers (CPDs) was measured in the dihydrofolate reductase (DHFR) gene and in a downstream nontranscribed genomic region. Pentoxifylli