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Characterization of recombinant human C1 inhibitor secreted in milk of transgenic rabbits

✍ Scribed by Harrie A. van Veen; Jaco Koiter; Carla J.M. Vogelezang; Noucha van Wessel; Tijtje van Dam; Ingeborg Velterop; Kristina van Houdt; Luc Kupers; Danielle Horbach; Mourad Salaheddine; Jan H. Nuijens; Maurice L.M. Mannesse

Book ID
118474089
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
750 KB
Volume
162
Category
Article
ISSN
0168-1656

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## Abstract **BACKGROUND:** Human erythropoietin (hEPO), a hydrophobic acidic glycoprotein responsible for the regulation of red blood cell production in mammals, is used for the treatment of anemia. In general, the purification of transgenic animal‐derived therapeutic proteins is not easy due to t