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Characterization of recombinant Bordetella pertussis adenylate cyclase toxins carrying passenger proteins

✍ Scribed by Sakina Gmira; Gouzel Karimova; Daniel Ladant

Book ID
117615203
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
218 KB
Volume
152
Category
Article
ISSN
0923-2508

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## Abstract The adenylate cyclase toxin–hemolysin (ACT) is a key virulence factor of the whooping cough agent __Bordetella pertussis__ (__Bp__). The major cytotoxic activity of this 1706‐residue protein consists of its capacity to invade a variety of eukaryotic cells directly across their cytoplasm