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Characterization of rat heart plasma membrane Ca2+/Mg2+ ATPase

โœ Scribed by Dayuan Zhao; Naranjan S. Dhalla


Book ID
115707968
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
893 KB
Volume
263
Category
Article
ISSN
0003-9861

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The purified Ca2+/Mg2+ ATPase from rat heart plasma membrane was activated by Ca2+ and Mg2+ with Ka values of 1.47 mM and 2.51 mM, respectively; other divalent cations also activated the enzyme but to a lesser extent. Divalent cations like Cu2+, Zn2+, Ni2+, Cd2+ were potent inhibitors of the enzyme