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Characterization of putative neurotransmitter N-acetyl-aspartyl-glutamic acid and some related compounds by fast atom bombardment and tandem mass spectrometry

✍ Scribed by Federico Maria Rubino; Luigi Zecca; Francesco Chillemi

Publisher: John Wiley and Sons
Year: 1992
Tongue: English
Weight: 493 KB
Volume: 21
Category: Article
ISSN: 1076-5174
DOI: 10.1002/bms.1200210205

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✦ Synopsis

The characterization of the N-blocked neuropeptide N-acetyl-aspartyl-glutamic acid and of some related compounds was carried out by negative-ion fast atom bombardment mass spectrometry and collision-induced dissociation of the generated [M-H]- species. Thorough analysis of the fragment ion spectra allowed discrimination between sequence isomeric compounds, and highlighting of differences between dipeptides linked in the normal or iso mode.

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