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Characterization of Presystemic Elimination of Trichloroethylene and Its Nonlinear Kinetics in Rats

โœ Scribed by K.M. Lee; J.V. Bruckner; S. Muralidhara; J.M. Gallo


Book ID
112266150
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
181 KB
Volume
139
Category
Article
ISSN
0041-008X

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Kinetics of biliary elimination of penta
โœ ล . Bezek; V. ล ฤasnรกr; M. Kukan; T. Trnovec ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 326 KB ๐Ÿ‘ 1 views

Pentacaine, a local anaesthetic of the carbanilate type, administered intravenously as 3H-pentacaine, 2 mg kg-' to rats, was eliminated in the bile mainly in the form of metabolites (20.5 f 1.5 per cent of the dose) and as parent drug (0.1 er cent of the dose) pentacaine metabolites, were excreted i