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Characterization of pre-β- and α-migrating HDL subfractions in Russian men with high and low HDL cholesterol level


Book ID
118631193
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
175 KB
Volume
3
Category
Article
ISSN
1567-5688

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Lecithin:cholesterol acyltransferase (LCAT) is crucial to the maturation of high-density lipoprotein (HDL). Homozygosity for LCAT mutations underlies rare disorders characterized by HDL-cholesterol (HDL-c) deficiency while heterozygotes have half normal HDL-c levels. We studied the prevalence of LCA