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Characterization of Polyion Complex Micelles Designed to Address the Challenges of Oligonucleotide Delivery

✍ Scribed by Marie-Hélène Dufresne; Mahmoud Elsabahy; Jean-Christophe Leroux

Publisher
Springer US
Year
2008
Tongue
English
Weight
247 KB
Volume
25
Category
Article
ISSN
0724-8741

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## Abstract Polyion complex micelles (PIC micelles) based on methoxy poly(ethylene glycol)‐__grafted__‐chitosan (mPEG‐__g__‐Chitosan) and lactose‐conjugated PEG‐__grafted__‐chitosan (Lac‐PEG‐__g__‐Chitosan) were designed as carriers for anionic drugs. Diammonium glycyrrhizinate (DG)‐loaded conventi