Syntheses and activities of backbone-sid
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Mohammad Safa Zoda; Martin Zacharias; Siegmund Reissmann
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Article
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2010
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John Wiley and Sons
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English
⚖ 310 KB
## Abstract The protein tyrosine phosphatase SHP‐1 plays an important role in many physiological and pathophysiological processes. This phosphatase is activated through binding of ligands to its SH2‐domains, mainly to the N‐terminal one. Based on a theoretical docking model, backbone‐to‐side chain