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Characterization of phosphotyrosine binding motifs in the cytoplasmic domain of B and T lymphocyte attenuator required for association with protein tyrosine phosphatases SHP-1 and SHP-2

✍ Scribed by Maya Gavrieli; Norihiko Watanabe; Susan K Loftin; Theresa L Murphy; Kenneth M Murphy


Book ID
116287573
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
248 KB
Volume
312
Category
Article
ISSN
0006-291X

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Syntheses and activities of backbone-sid
✍ Mohammad Safa Zoda; Martin Zacharias; Siegmund Reissmann 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 310 KB

## Abstract The protein tyrosine phosphatase SHP‐1 plays an important role in many physiological and pathophysiological processes. This phosphatase is activated through binding of ligands to its SH2‐domains, mainly to the N‐terminal one. Based on a theoretical docking model, backbone‐to‐side chain