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Characterization of Phospholamban Mutants Implicated in Dilated Cardiomyopathy

✍ Scribed by Vostrikov, Vitaly V.; Veglia, Gianluigi


Book ID
122326067
Publisher
Biophysical Society
Year
2013
Tongue
English
Weight
35 KB
Volume
104
Category
Article
ISSN
0006-3495

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## Communicated by Nancy B. Spinner Depressed calcium handling by the sarcoplasmic reticulum (SR) Ca-ATPase and its regulator phospholamban (PLN) is a key characteristic of human and experimental heart failure. Accumulating evidence indicates that increases in the relative levels of PLN to Ca-ATPa