Polymorphisms of CYP450 metabolizer enzymes and transport proteins play crucial roles in the interβindividual variability of drug efficiency. The aim of our study was to predict the frequency of functional variants of __CYP2D6__, __CYP2C19__ and __ABCB1__ genes in the Hungarian population. One hundr
β¦ LIBER β¦
Characterization of pharmacogenetically relevant CYP2D6 and ABCB1 gene polymorphisms in a Portuguese population sample
β Scribed by C. Correia; P. Santos; A. M. Coutinho; A. M. Vicente
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 74 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0263-6484
- DOI
- 10.1002/cbf.1561
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## Abstract Alterations in dopaminergic system have been implicated in the pathophysiology of this disease for many years, and this study was performed to assess the possible involvement of the dopamine D4 receptor (__DRD4__) gene polymorphisms either in the 5β² upstream or in the coding regions, in