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Characterization of peptide aptamers to the Anterior Gradient 2: a novel inhibitor of the tumour suppressor protein p53

✍ Scribed by A Fourtouna, E Murray, L Hayward, L Pohler, T Hupp


Book ID
120700235
Publisher
BioMed Central
Year
2006
Tongue
English
Weight
325 KB
Volume
8
Category
Article
ISSN
1465-5411

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## Abstract The p53 tumor suppressor gene, which is frequently mutated in a wide variety of tumors, plays an important role in maintaining genomic integrity. Following genotoxic insults, the protein level of p53 is increased, and p53 functions as a sequence‐specific transcription factor that regula