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Characterization of P53 activities in cervial carcinoma cells with and without HPV oncogene expression

✍ Scribed by F. Aengeneyndt; D. Spitkovsky; M. von Knebel Doeberitz

Book ID
112784806
Publisher
Springer-Verlag
Year
1995
Tongue
English
Weight
137 KB
Volume
121
Category
Article
ISSN
1432-1335

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Mutations within the tumor suppressor genes Rb-1 and p53 are commonly found in many human malignancies, and loss of wild-type function of both p53 and RB appear to be important events in the development of these malignancies. Interference with normal RB and p53 function in the cell has apparently al