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Characterization of nuclear factors binding to AT-rich element in the rat p53 promoter

✍ Scribed by Minhyung Lee; Sunhee Yu; Young-sam Lee; Jong-sang Park


Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
210 KB
Volume
80
Category
Article
ISSN
0730-2312

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We previously reported that two nuclear factor 1-like elements mediated the transcription of the rat p53 gene. A 40-kDa protein was shown to bind to these elements, which was different from common NF1 family proteins. In this study, the biochemical properties of the 40-kDa binding protein were inves

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## Abstract Hepatic nuclear protein has been reported to bind specifically to the TTGGC sequence of the rat regucalcin gene promoter region in stimulating the promoter activity (Misawa and Yamaguchi [2000] Biochem. Biophys. Res. Commun. 279: 275–281). The present study was undertaken to identify tr